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  • On September 26, UCLA researcher reported the outcomes of a study, which indicated that Asians who are struggling with alcoholism will benefit especially from naltrexone, certainly one of three medications authorized by the U.S. Food and Drug Administration (FDA) to the treatment of alcoholism. Recent research has found out that a gene variant may predict naltrexone treatment success for alcoholism. About 50% of patients of Asian descent possess a particular mutation that produces them likely to benefit from naltrexone, compared with about 20% of Caucasians and less than 5% of African Americans, said lead study author Lara Ray, an assistant professor of psychology and director with the UCLA Addictions Laboratory. The findings are still available online ( within the journal Neuropsychopharmacology and will be published in the upcoming print edition of the journal.

    Using two separate drugs to shed pounds can be very effective you will find combinations before the FDA now awaiting approval. When dealing with weight reduction and the individuals who go through it you ought to err to the side of caution and allow the FDA do its job and demand some study be done so your public is aware of the side effects and perils associated with the medications before we take them. Keep in mind that drug companies will be in business to make money and that they would say anything to keep people on his or her medications.

    Researchers found that participants taking this drug for a year, lost weight within four weeks and have kept the body weight off during the entire 56 weeks in the study. Contrave is often a combination with the drugs naltrexone and bupropion, which generally seems to reflect a fresh trend of weight-loss drugs which can be made up of multiple active ingredient, that might make them far better and safer.

    Combo-pilling could be the newest fad or also the newest in the future under scrutiny and thus it is just more publicly known lately, comb-pilling for losing weight has been around since the eighties. The biggest reason that employing a combination of pills is becoming popular could be the fact that as of right now there aren't long term prescription weight loss supplements that have been licensed by the FDA besides orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications although some people might of the combinations have been rejected or have yet to be authorized by the FDA.

    Seizures certainly are a side effect with Contrave and really should not be taken in people who have seizure disorders. The drug also can raise blood pressure levels and heartrate, and mustn't be used in people who have a history of cardiac arrest or stroke in the last six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with all the drug.

    The FDA also warned that Contrave can raise blood pressure level and heart rate and must not be used in patients with uncontrolled high blood pressure, in addition to by you are not heart-related and cerebrovascular (circulation dysfunction impacting the brain) disease. Patients having a history of cardiac arrest or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes which has a boxed warning to alert medical professionals and patients on the increased risk of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for quitting smoking.

    "This could be the first drug I'm aware of that targets the appetite and reward centres in the brain," he said.