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  • On September 26, UCLA researcher reported the outcome of a study, which indicated that Asians who are struggling with alcoholism will benefit especially from naltrexone, certainly one of three medications licensed by the U.S. Food and Drug Administration (FDA) to the treatment of alcoholism. Recent research has found that a gene variant may predict naltrexone treatment success for alcoholism. About 50% of patients of Asian descent use a particular mutation that produces them more likely to benefit from naltrexone, weighed against about 20% of Caucasians and fewer than 5% of African Americans, said lead study author Lara Ray, an assistant professor of psychology and director with the UCLA Addictions Laboratory. The findings are currently available online ( in the journal Neuropsychopharmacology and will also be published within an upcoming print edition in the journal.

    Using two separate drugs to lose weight can be very effective you will find combinations before the FDA now awaiting approval. When dealing with weight loss and the those who go through it you need to err along the side of caution and permit the FDA do its job and demand some study be done so your public recognizes the side effects and risks of the medications before we bring them. Keep in mind that drug companies come in business to generate money and that they would say anything to keep people on the medications.

    Researchers discovered that participants using this drug to get a year, dropped excess weight within four weeks and have kept the load off through the entire 56 weeks of the study. Contrave is really a combination in the drugs naltrexone and bupropion, which seems to reflect a brand new trend of weight-loss drugs which can be made up of more than one active ingredient, which may make them more potent and safer.

    Combo-pilling may be the newest fad or even better the newest ahead under scrutiny and for that reason it is just more publicly known although in the past, comb-pilling for weight loss has been around since the eighties. The biggest reason that utilizing a combination of pills is starting to become popular could be the fact that at the time of right now there are not any long term prescription slimming capsules that have been approved by the FDA apart from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications and some of the combinations are actually rejected or have yet to be approved by the FDA.

    Seizures are a side effect with Contrave and really should not be taken in individuals with seizure disorders. The drug also can raise blood pressure and pulse rate, and really should not be used in those with a history of cardiac arrest or stroke in the last six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy using the drug.

    The FDA also warned that Contrave can raise hypertension and heartrate and must not used in patients with uncontrolled high blood pressure levels, along with by a person with heart-related and cerebrovascular (blood vessel dysfunction impacting mental performance) disease. Patients using a history of cardiac arrest or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes which has a boxed warning to alert medical researchers and patients on the increased probability of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for quitting smoking.

    Approving a drug using this many potentially lethal side effects is inconsistent using the mission statement from the FDA. The power from the drug manufacturing lobby is blatantly evident inside approval of several drugs requiring 'post-marketing' studies which might be clearly significant to overall drug safety within the US.