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    Researchers found out that participants using this drug to get a year, dropped excess weight within four weeks and have kept the weight off through the entire 56 weeks from the study. Contrave is often a combination of the drugs naltrexone and bupropion, which generally seems to reflect a fresh trend of weight-loss drugs which are made up of several active ingredient, which can make them more potent and safer.

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    Seizures can be a side effect with Contrave and mustn't be taken in people with seizure disorders. The drug may also raise hypertension and heart rate, and mustn't be used in people with a history of heart attack or stroke in the previous six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy with the drug.

    The FDA also warned that Contrave can raise hypertension and heart rate and must not be used in patients with uncontrolled high hypertension, in addition to by a person with heart-related and cerebrovascular (blood vessel dysfunction impacting your brain) disease. Patients having a history of heart attack or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes which has a boxed warning to alert health care professionals and patients towards the increased likelihood of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stopping smoking.

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