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  • On September 26, UCLA researcher reported the outcome of a study, which indicated that Asians who're struggling with alcoholism will benefit especially from naltrexone, certainly one of three medications approved by the U.S. Food and Drug Administration (FDA) to the treatment of alcoholism. Recent research has found that a gene variant may predict naltrexone treatment success for alcoholism. About 50% of patients of Asian descent have a very particular mutation that makes them prone to benefit from naltrexone, weighed against about 20% of Caucasians and fewer than 5% of African Americans, said lead study author Lara Ray, an assistant professor of psychology and director of the UCLA Addictions Laboratory. The findings are presently available online ( in the journal Neuropsychopharmacology and are published in an upcoming print edition of the journal.

    Using two separate drugs to lose weight can be very effective there are combinations before the FDA now awaiting approval. When dealing with fat loss and the people that go through it you should err to the side of caution and allow FDA do its job and demand some research be done in order that the public understands the side effects and dangers of the medications before we bring them. Keep in mind that drug companies will be in business to earn money and that they would say anything to keep people on their own medications.

    Researchers discovered that participants taking this drug for the year, lost weight within 4 weeks and have kept the weight off throughout the 56 weeks with the study. Contrave is really a combination with the drugs naltrexone and bupropion, which generally seems to reflect a fresh trend of weight-loss drugs which are made up of multiple active ingredient, that might make them more effective and safer.

    Combo-pilling is the newest fad or even better the newest ahead under scrutiny and so it is just more publicly known lately, comb-pilling to lose weight has been around since the eighties. The biggest reason that using a combination of pills is now popular may be the fact that by right now there are not any long term prescription weightloss pills that have been approved by the FDA besides orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications and some of the combinations are already rejected or have yet to be authorized by the FDA.

    Seizures really are a side effect with Contrave and really should not be taken in people who have seizure disorders. The drug could also raise blood pressure and heart rate, and must not be used in individuals with a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy while using drug.

    The FDA also warned that Contrave can raise hypertension and heart rate and must 't be used in patients with uncontrolled high blood pressure, along with by a person with heart-related and cerebrovascular (circulation dysfunction impacting the mind) disease. Patients which has a history of heart attack or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes using a boxed warning to alert medical professionals and patients towards the increased probability of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for smoking cessation.

    Most of the combinations which are used to enhance weight reduction involve an amphetamine as well as an antidepressant. Phentermine and Prozac are a popular combination that were around for quite a while, and although it has been around stuffed to truly combine both and try to get FDA approval to promote it as a weight-loss pill. Right there should raise some warning flag if the greedy pharmaceutical companies should not be involved in combining medications and selling them something have to be wrong with all the combination. In fairness there exists one weight loss combination pill that is certainly in front of the FDA now Contrave?which couples naltrexone, utilized to treat alcohol and substance abuse, using the antidepressant bupropion (Wellbutrin, Zyban) many experts have given the just do it to move forward by an FDA advisory committee, but as of yet is not approved.