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  • Evidence is increasing that addiction without exception is related to issues with the brain's reward center, especially the mesolimbic system. This the main problem regulates reward responses in establishing food and sex, plus nurturing infants and children. One of the most important neurotransmitters associated with reward responses, both when they malfunction and whenever they function properly, is dopamine. What makes opiates unique is that it, among other neurotransmitters modulates "the volume of dopamine released in in response to a stimulus"(Bostwick & Bucci, 2008).

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    Seizures really are a side effect with Contrave and really should not be taken in those with seizure disorders. The drug could also raise blood pressure and heart rate, and really should not be used in individuals with a history of cardiac arrest or stroke in the last six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy using the drug.

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    From a psychiatric viewpoint, evidence shows that the ordinary neural mechanism for goal-directed behavior has become hijacked with the addiction, and malfunctions so that its ordinary functions are exaggerated and fixated on its object. An object produces a stimulus along with the person engages in a "goal-directed behavioral response" that produces a "natural high"(Bostwick & Bucci, 2008).